Herpes Simplex is a viral disease caused by two different viruses: Herpes Simplex Virus 1 (HSV-1) and Herpes Simplex Virus 2 (HSV-2). HSV-1 is the most common cause of oral herpes, which manifests as painful sores or blisters around the mouth. HSV-2 most commonly causes genital herpes, which manifests as painful sores in the genital area. The virus is transmitted through direct contact with the affected part of the body, either through kissing or sexual intercourse. Herpes cannot be cured, and outbreaks usually recur. Herpes outbreaks can be treated with antiviral medications.