It is about antibodies (immunoglobulins A - IgA). EMA is an acronym for endomysial antibodies, which are specific for celiac disease, an autoimmune disease that causes problems with gluten digestion. The S-EMA IgA test is used to detect celiac disease, as an elevated level of these antibodies in the blood is often a sign of this disease. If the S-EMA IgA test is positive, it is a strong indicator of the presence of celiac disease, but to confirm the diagnosis, an additional examination is usually needed, such as a biopsy of the small intestine.