IgE is an acronym for Immunoglobulin E. IgE is produced by cells called plasma cells. IgE plays an important part in the immune response. They play a role in defending the body against parasites. IgE also plays a significant role in type I hypersensitivity, which we encounter in asthma, allergic rhinitis, food allergies, and atopic dermatitis. IgE also plays a significant role in severe allergic reactions such as anaphylactic reaction.