The skin barrier is the outer layer of the skin, which acts as a boundary between the external environment and the internal environment of the body. The skin barrier is composed of skin cells and fats, as well as numerous other substances (e.g. antimicrobial peptides). Part of the skin barrier are also "good" microorganisms (the most numerous are bacteria), which protect the skin from harmful microorganisms. If the skin barrier is weakened, as is the case with atopic dermatitis, the skin becomes inflamed, itchy, peels off, and also more often leads to various infections.